I have a DSB and yes they are a bugger to get going but once working they are fantastic. I have combined mine with an algae scrubber.
Contact
www.stm-shop.co.uk and ask for advice about the best sand to use and how to seed the filter I'm sure they would be more than willing to help as they use DSB's in their systems.
The minimum depth of sand is said to be 4" I have opted for about 7".
Once up and running they are fantastic mine is absolutely full of life within the caulerpa I have thousands of critters swimming about and in the sand I have a whole host of different types of worms predominantly bristle worms even right at the bottom of the sand bed.
The trick for getting them to work is getting the critters in there as quickly as possible before the sand bed goes black, if it goes black that area is dead. In order to prevent this from happening you need to push the handle of a teaspoon to the bottom of the sand bed and then twist it this enables oxygen rich water to get to the base of the sand bed.
The aim is to create a slightly anaerobic environment that facilitates the slow uptake of nitrate as well as ammonia and nitrite. As a test of the effectiveness of the system I ran my reef for 6 months without a water change and monitored the situation closely nitrate peaked at 15 ppm.
Send me a pm with your concerns and I will see what I can come up with.